Googling the cancer genome
Identification and prioritization of cancer-causing structural variations in patient-derived whole genome sequencing data
Highly portable parallel workflow to generate artificial genomes with structural variants.
This Snakemake-based workflow generates artificial short-read alignments based on a reference genome with(out) SVs. The workflow is easy to use and deploy on any Linux-based machine. In particular, the workflow supports automated software deployment, easy configuration and addition of new analysis tools as well as enables to scale from a single computer to different HPC clusters with minimal effort.