A node for the KNIME workflow systems that allows you to identify which residue position in a big protein sequence alignment is specific to ligand binding.
For bioinformaticians or cheminformaticians who have no 3D structure of their protein, just a protein sequence and want to know which position is likely to bind a ligand.
It takes a big multi species multiple sequence alignment and a list of subfamily members to produce a score for each position in the sequence alignment.
Can tell which residue in a protein is likely to bind a ligand without 3D information